|
KMID : 1134120190220030491
|
|
Journal of Breast Cancer
2019 Volume.22 No. 3 p.491 ~ p.496
|
|
|
Primary Histiocytic Sarcoma Presenting as a Breast Mass: A Case Report
|
|
Bang Seong-Sik
Kim Ye-Seul
Chung Min-Sung
Park Jeong-Seon
Choi Yun-Young
Shin Su-Jin
|
|
|
Abstract
|
|
|
|
Histiocytic sarcoma is a rare hematologic malignancy, with very few cases of primary histiocytic sarcoma of the breast described in English scientific literature. Herein, we describe a case of primary histiocytic sarcoma of the breast in a 75-year-old woman, with no clinical history of malignant tumors, who presented with a palpable solitary breast mass. Microscopically, the resected breast mass showed large pleomorphic cells, some multinucleated giant cells, and admixed inflammatory components. The pleomorphic tumor cells further showed a diffuse, noncohesive growth pattern, an abundant eosinophilic cytoplasm, and strong and diffuse immunoreactivity for cluster of differentiation (CD) 68 and CD163. Furthermore, a whole-body positron-emission tomography/computed tomography using deoxy-2-[18F]fluoro-D-glucose performed after surgery showed no other masses or lesions. After surgical excision, the patient was followed up, and no evidence of tumor recurrence or metastasis was noted.
|
|
|
KEYWORD
|
|
|
Breast, Histiocytes, Histiocytic sarcoma, True histiocytic lymphoma
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
   
|
|